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Abstracts | Clinical Trials

Mast Stem Cell Therapy

Abstracts & Clinical Trials on Adult Stem Cell Therapy

Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells. (Bone. 2012 Jan;50(1):325-30. Epub 2011 Nov 7.)

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Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: Five year follow-up of a prospective controlled study. (Bone. 2011 Nov;49(5):1005-9. Epub 2011 Jul 29.)

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Treatment of Jones fracture nonunions and refractures in the elite athlete: outcomes of intramedullary screw fixation with bone grafting. (Am J Sports Med. 2011 Sep;39(9):1948-54. Epub 2011 Jun 1)

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Percutaneous internal fixation of proximal fifth metatarsal jones fractures (Zones II and III) with Charlotte Carolina screw and bone marrow aspirate concentrate: an outcome study in athletes. (Am J Sports Med. 2011 Jun;39(6):1295-301. Epub 2011 Jan 6)

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Autologous bone marrow grafting combined with demineralized bone matrix improves consolidation of docking site after distraction osteogenesis. (J Bone Joint Surg Am. 2011 Apr 6;93(7):671-8.)

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Bone grafting in surgery about the foot and ankle: indications and techniques. (J Am Acad Orthop Surg. 2011 Feb;19(2):112-20.)

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Bridging the gap: bone marrow aspiration concentrate reduces autologous bone grafting in osseous defects. (J Orthop Res. 2011 Feb;29(2):173-80. doi: 10.1002/jor.21230. Epub 2010 Aug 25.)

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Use of collagen scaffold and autologous bone marrow concentrate as a one-step cartilage repair in the knee: histological results of second-look biopsies at 1 year follow-up. (Int J Immunopathol Pharmacol. 2011 Jan-Mar;24(1 Suppl 2):69-72.)

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Mesenchymal Progenitor Cells and Their Orthopedic Applications: Forging a Path towards Clinical Trials. (Stem Cells Int. 2010 Dec 16;2010:519028.)

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Stem cells in bone grafting: Trinity allograft with stem cells and collagen/beta-tricalcium phosphate with concentrated bone marrow aspirate. (Foot Ankle Clin. 2010 Dec;15(4):611-9.)

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Injection of demineralized bone matrix with bone marrow concentrate improves healing in unicameral bone cyst. (Clin Orthop Relat Res. 2010 Nov;468(11):3047-55.)

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Treatment of chondral defects of the knee with one step matrix-assisted technique enhanced by autologous concentrated bone marrow: in vitro characterisation of mesenchymal stem cells from iliac crest and subchondral bone. (Injury. 2010 Nov;41(11):1172-7. Epub 2010 Oct 8.)

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Regenerative facial reconstruction of terminal stage osteoradionecrosis and other advanced craniofacial diseases with adult cultured stem and progenitor cells. (Plast Reconstr Surg. 2010 Nov;126(5):1699-709.)

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Phases 1-3 clinical trials using adult stem cells in osteonecrosis and nonunion fractures. (Stem Cells Int. 2010 Oct 26;2010:410170.)

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Healos graft carrier with bone marrow aspirate instead of allograft as adjunct to local autograft for posterolateral fusion in degenerative lumbar scoliosis: a minimum 2-year follow-up study. (J Neurosurg Spine. 2010 Aug;13(2):211-5.)

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Treatment of nontraumatic osteonecrosis of the femoral head with the implantation of core decompression and concentrated autologous bone marrow containing mononuclear cells. (Arch Orthop Trauma Surg. 2010 Jul;130(7):859-65. Epub 2009 Jul 21.)

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Fixed intramedullary nailing and percutaneous autologous concentrated bone-marrow grafting can promote bone healing in humeral-shaft fractures with delayed union. (Injury. 2010 Jun;41(6):563-7. Epub 2009 Sep 9.)

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Bone morphogenetic protein-2 and bone marrow aspirate with allograft as alternatives to autograft in instrumented revision posterolateral lumbar spinal fusion: a minimum two-year follow-up study. (Spine (Phila Pa 1976). 2010 May 15;35(11):1144-50.)

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Treatment for unicameral bone cysts in long bones: an evidence based review. (Orthop Rev (Pavia). 2010 Mar 20;2(1):e13.)

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Transpedicular aspiration of osteoprogenitor cells from the vertebral body: progenitor cell concentrations affected by serial aspiration. (Spine J. 2009 Dec;9(12):995-1002.)

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A comparison of posterolateral lumbar fusion comparing autograft, autogenous laminectomy bone with bone marrow aspirate, and calcium sulphate with bone marrow aspirate: a prospective randomized study. (Spine (Phila Pa 1976). 2009 Dec 1;34(25):2715-9.)

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Complications associated with autogenous bone marrow aspirate harvest from the lower extremity: an observational cohort study. ( J Foot Ankle Surg. 2009 Nov-Dec;48(6):668-71. Epub 2009 Aug 26.)

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Safety of autologous bone marrow aspiration concentrate transplantation: initial experiences in 101 patients. ( Orthop Rev (Pavia). 2009 Oct 10;1(2):e32.)

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Macroscopic and histologic analyses of de novo bone in the posterior spine at time of spinal implant removal. (J Spinal Disord Tech. 2009 Aug;22(6):434-8.)

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Clinical and radiographic assessment of transforaminal lumbar interbody fusion using HEALOS collagen-hydroxyapatite sponge with autologous bone marrow aspirate. (Spine J. 2009 Jun;9(6):434-8. Epub 2008 Dec 25.)

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Application of a new chair-side method for the harvest of mesenchymal stem cells in a patient with nonunion of a fracture of the atrophic mandible--a case report. (J Craniomaxillofac Surg. 2009 Apr;37(3):155-61. Epub 2009 Jan 19.)

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Use of platelet-rich concentrate and bone marrow aspirate in high-risk patients with Charcot arthropathy of the foot. (Foot Ankle Int. 2009 Feb;30(2):124-7.)

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Autologous bone marrow graft and treatment of delayed and non-unions of long bones: technical aspects. (Biomed Mater Eng. 2009;19(4-5):277-81.)

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Bone marrow concentrate: a novel strategy for bone defect treatment. (Curr Stem Cell Res Ther. 2009 Jan;4(1):34-43.)

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Use of autologous bone marrow cells concentrate enriched with platelet-rich fibrin on corticocancellous bone allograft for posterolateral multilevel cervical fusion. (J Tissue Eng Regen Med. 2008 Dec;2(8):515-20.)

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Unicameral bone cyst: a retrospective study of three surgical treatments. (Clin Orthop Relat Res. 2008 Oct;466(10):2519-26. Epub 2008 Aug 5.)

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Percutaneous bone marrow aspirate and bone graft harvesting techniques in the lower extremity. (Clin Podiatr Med Surg. 2008 Oct;25(4):733-42, x.

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The outcome of composite bone graft substitute used to treat cavitary bone defects. (Orthopedics. 2008 Aug;31(8):754.)

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Cell based bone tissue engineering in jaw defects. (Biomaterials. 2008 Jul;29(21):3053-61. Epub 2008 Apr 22.)

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A histomorphogenic analysis of bone grafts augmented with adult stem cells. (Implant Dent. 2007 Mar;16(1):42-53.)

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Bone block allograft impregnated with bone marrow aspirate. (Implant Dent. 2007 Dec;16(4):329-39.)

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Multilevel anterior cervical fusion using a collagen-hydroxyapatite matrix with iliac crest bone marrow aspirate: an 18-month follow-up study. (Neurosurgery. 2007 Nov;61(5):963-70; discussion 970-1.)

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Demineralized bone matrix composite grafting for posterolateral spinal fusion. (Orthopedics. 2007 Jul;30(7):567-70.)

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Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions? (Injury. 2007 Mar;38 Suppl 1:S75-80.)

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Effect of bone marrow grafting on the titanium porous-coated implant in bilateral total knee arthroplasty. (Acta Orthop. 2007 Feb;78(1):116-22.)

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Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells. (Osteoarthritis Cartilage. 2007 Feb;15(2):226-31. Epub 2006 Sep 26.)

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Percutaneous autologus bone marrow injection in the treatment of delayed or nonunion. (Indian J Orthop. 2007 Jan;41(1):67-71.)

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Instrumented fusion of thoracolumbar fracture with type I mineralized collagen matrix combined with autogenous bone marrow as a bone graft substitute: a four-case report. (Eur Spine J. 2006 Oct;15 Suppl 5:630-5. Epub 2006 Jul 25.)

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Grafting long bone fractures with demineralized bone matrix putty enriched with bone marrow: pilot findings. (Orthopedics. 2006 Oct;29(10):939-41.)

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Percutaneous autologous bone-marrow grafting for nonunions. Surgical technique. (J Bone Joint Surg Am. 2006 Sep;88 Suppl 1 Pt 2:322-7.)

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Healos and bone marrow aspirate used for lumbar spine fusion: a case controlled study comparing healos with autograft. (Spine (Phila Pa 1976). 2006 Aug 15;31(18):E636-40.)

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A preliminary comparative study of radiographic results using mineralized collagen and bone marrow aspirate versus autologous bone in the same patients undergoing posterior lumbar interbody fusion with instrumented posterolateral lumbar fusion. (Spine J. 2006 Jul-Aug;6(4):405-11; discussion 411-2.)

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Fresh bone marrow and periosteum transplantation for cartilage defects of the knee. (Transplant Proc. 2006 Jan-Feb;38(1):318-9.)

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Treatment of aneurysmal bone cysts by introduction of demineralized bone and autogenous bone marrow. (J Bone Joint Surg Am. 2005 Oct;87(10):2253-8.)

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Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells. (J Bone Joint Surg Am. 2005 Jul;87(7):1430-7.)

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Percutaneous bone marrow grafting for the treatment of tibial non-union. (Injury. 2005 Jan;36(1):203-6.)

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Aspiration of osteoprogenitor cells for augmenting spinal fusion: comparison of progenitor cell concentrations from the vertebral body and iliac crest. (J Bone Joint Surg Am. 2005 Dec;87(12):2655-61.)

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The role and effectiveness of bone marrow in osseous regeneration. (Med Hypotheses. 2005;65(4):740-7.)

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Autologous bone marrow stromal cell transplantation for repair of full-thickness articular cartilage defects in human patellae: two case reports. (Cell Transplant. 2004;13(5):595-600.)

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Comparison of bone grafts for posterior spinal fusion in adolescent idiopathic scoliosis. (Spine (Phila Pa 1976). 2003 Apr 15;28(8):793-8.)

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Bone graft alternatives for spinal fusion. (BioDrugs. 2003;17(6):391-4.)

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A composite bone graft substitute for anterior cervical fusion: assessment of osseointegration by quantitative computed tomography. (Spine (Phila Pa 1976). 2002 May 15;27(10):1037-43.)

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Role of percutaneous bone marrow grafting in delayed unions, non-unions and poor regenerates. (Indian J Med Sci. 2001 Jun;55(6):326-36.)

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Autogenic bone marrow injections as a treatment for simple bone cyst. (J Pediatr Orthop. 1998 Sep-Oct;18(5):616-20.)

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Percutaneous autologous bone marrow transplantation for nonunion of the femur. (Nihon Geka Hokan. 1998 Mar 1;67(1):10-7.)

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Autologous marrow injection in the treatment of delayed and non-union in long bones. (Singapore Med J. 1993 Oct;34(5):412-7.)

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Percutaneous bone marrow grafting of delayed union and nonunion in cancer patients. (Clin Orthop Relat Res. 1990 Jul;(256):280-5.)

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Use of xenograft bone with aspirated bone marrow for treatment of cystic defect of the jaws. (Head Neck. 1989 Nov-Dec;11(6):516-23.)

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